In last decade, there has been a rapid advancement in the utilization of percutaneous, image-guided tumor ablation methods. Radio frequency (RF) ablation has become the method of choice because of its safety and efficacy.Image-guided RF ablation is minimally invasive and usually appropriate for inoperable patients with other comorbidities.
It requires a minimal hospital stay or can be performed on an outpatient basis. It preserves more normal organ tissue and is less expensive than surgery
Lung cancer is the leading cause of cancer – related death in both men and women, and NSCLC accounts for the majority of the cases. Although surgery provides the best possibility for a cure in early stages (I/II) of NSCLC, the majority of these patients have insufficient cardiopulmonary reserve and thus are not surgical candidates (31, 32). RF ablation, alone or in combination with other treatment modalities such as external beam radiation, is an alternative option for these patients and is currently the most commonly utilized thermal ablation method with promising survival data; 68% for two year survival (10) and 74% for three year survival for Radio frequency ablation of lung tumors in Bangalore.
RF ablation can also be used in patients with metastatic lung disease for eradication of small tumors (<3 cm) limited in number or for palliation of larger tumors that cause symptoms such as cough, hemoptysis, or pain (5). A recent prospective, intent-to-treat multi-center clinical trial studied 106 patients with 183 primary or secondary lung tumors smaller than 3.5 cm, which had been treated with RF ablation. Cancer-specific survival rates at one and two years were 92% and 73%, respectively, for patients with NSCLC, 91% and 68%, respectively, for patients with colorectal metastases, and 93% and 67%, respectively, for patients with other metastases (4). Crocetti and Lencioni (33) also reported a complete ablation rate of approximately 80% in tumors smaller than 3.5 cm in size for Radio frequency ablation of lung tumors in Bangalore.
Pulmonary RF ablation is a safe procedure with a reported mortality of 0.4% (34) and an overall major complication rate ranging between 8% and 12% (35). Pneumothorax is the most common complication (~20%). Small pleural effusions are frequent and generally self-limited. Productive cough with brown sputum occurs in a minority of patients and may last 1–2 weeks. Peripheral, pleural based tumors or tumors surrounded by normal lung parenchyma are best suited for Radio Frequency ablation. Central tumors located close to the central airway carry a risk of injury of the bronchus, resulting in cavitation,
abscess formation, and bronchopleural fistula for Radio frequency ablation of lung tumors in Bangalore