Best colon cancer treatment doctor in Bangalore
Dr Adarsh M Patil mbbs ms Is one of the leading cancer surgeons in Bangalore .
15 years of experience in eminent hospitals like Manipal Hospital, Apollo Hospitals and Narayana Hrudalaya in Bangalore.
He has experience of treating numerous colon cancer patients in Bangalore successfully .
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The incidence of colorectal cancer in the United States has been stable since the 1950s, with 145,000 new cases (105,000 colon and 40,000 rectal) each year and 58,000 deaths each year. It is the third-most-lethal cancer in men and women, with a slight female predominance in colon cancer and male predominance in rectal cancer. Colon cancer treatment Bangalore -There is a 5% lifetime risk; 6% to 8% of cases occur before age 40 years, and the incidence increases steadily after age 50 years.
Signs & Symptoms of colon cancer.
Depends on the location of the lesion. Many tumors are asymptomatic and discovered on routine screening colonoscopy. Right-colon lesions occasionally cause hematochezia, but more often bleeding is occult, causing anemia and fatigue. Left-colon lesions more often cause crampy abdominal pain, altered bowel habit, or hematochezia. In less than 10% of cases, left-colon cancer presents as large-bowel obstruction with inability to pass flatus or feces, abdominal pain, and distention. Approximately 50% of patients with other symptoms complain of weight loss, but weight loss is almost never the sole manifestation of a colorectal tumor. Rarely, colon cancer presents as perforation with focal or diffuse peritonitis or as a fistula with pneumaturia or feculent vaginal discharge. These symptoms may be difficult to distinguish from those of diverticulitis. Metastatic disease is usually asymptomatic but may present with jaundice, pruritus, and ascites or with cough and hemoptysis.
Diagnosis and staging
Once the diagnosis is suspected based on history, physical examination, or screening tests, every attempt should be made to obtain biopsy of the primary lesion and rule out synchronous cancer (3% to 5%). Colonoscopy to the cecum or flexible sigmoidoscopy and barium enema are acceptable for colon cancer treatment Bangalore. In patients presenting with obstructive symptoms, water-soluble contrast enema is performed to assess the degree and level of obstruction and to “clear” the colon proximal to the obstruction in colon cancer treatment Bangalore.
Staging studies to look for distant metastases include chest x-ray and abdominal CT scan. CT identifies liver metastases as well as adrenal, ovarian, pelvic, and lymph node metastases. Serum carcinoembryonic antigen (CEA) is a useful prognostic and surveillance tumor marker in colon cancer treatment Bangalore. CEA should be obtained preoperatively as part of the staging evaluation. Recently, positron emission tomography (PET)-CT has been shown to have greater sensitivity for detecting metastatic disease than CT alone. It is routinely performed prior to concurrent colectomy and liver resection for hepatic metastases.
Dr Adarsh M Patil mbbs ms Is one of the leading cancer surgeons in Bangalore .
15 years of experience in eminent hospitals like Manipal Hospital, Apollo Hospitals and Narayana Hrudalaya in Bangalore.
He has experience of treating numerous colon cancer patients in Bangalore successfully .
Colon cancer surgery in Bangalore
Open operative technique begins with a thorough exploration that includes palpation of the liver. After mobilization of the involved segment, the main segmental vessels are then ligated and divided, and en bloc resection of colon and any adherent structure is carried out, including small bowel, ovaries, uterus, or kidney. If curative resection is not possible, palliative resection should be attempted, and if this cannot be done, bypass should be performed for colon cancer treatment Bangalore.
Laparoscopic surgery for colon cancer in Bangalore
Offers a shorter hospital stay and faster recovery for patients with colon cancer. Oncologically, it is guided by the same principles as open resection. The Clinical Outcomes of Surgical Therapy (COST) trial demonstrated noninferiority of the laparoscopic approach as compared to open surgery, with statistically similar times to tumor recurrence, wound implantation, and overall survival at 4.5 years (N Engl J Med 2004;350:2050). This multicenter trial of 872 patients is commendable for the strict requirement of surgeon credentialing prior to enrolling patients, including video review of operative technique by a panel of experts.
Staging and prognosis of colon cancer treatment in Bangalore.
The American Joint Committee on Cancer TNM staging identifies the depth of invasion of the tumor (T), regional lymph node status (N), and presence of distant metastases (M). Stage I (T1 or T2, N0, M0) tumors do not involve the muscularis and have a 90% 5-year survival. Stage II (T3 or T4, N0, M0) tumors penetrate the muscularis and have a 60% to 80% 5-year survival. Stage III (Tx, N1 or N2, M0) tumors involve lymph nodes and have a 60% 5-year survival. Stage IV (Tx, Nx, M1) tumors have distant metastases and a 5-year survival of 10%. Unfavorable characteristics include poor differentiation, mucinous or signet-ring pathology, venous or perineural invasion,bowel perforation, aneuploid nuclei, and elevated carcinoembryonic antigen (CEA).
Adjuvant chemotherapy remains a standard treatment for stage III and IV colon cancer. Current regimens involve the combination of 5-fluorouracil/leucovorin with either irinotecan (FOLFIRI) or oxaliplatin (FOLFOX). The role of targeted therapy using vascular endothelial growth factor (VEGF) inhibitors (bevacizumab) or epidermal growth factor receptor (EGFR) inhibitors (cetuximab) is evolving. Patients with stage IIb tumors with poor prognostic factors may also benefit from adjuvant chemotherapy, although the risk-to-benefit ratio is not as great.
Follow-up is crucial in the first 2 years after surgery, when 90% of recurrences occur. Surveillance colonoscopy is recommended the first year after resection and then every 3 years until negative, at which time every 5 years is recommended. CEA should be checked in the first year, and rising levels should prompt a CT scan, a chest x-ray, and a PET scan to detect and stage recurrence.
Cost of Colon cancer treatment in Bangalore India
Average cost may vary between 150000 to 250000 INR based on type of hospital .
Dr Adarsh M Patil mbbs ms Is one of the leading cancer surgeons in Bangalore .
15 years of experience in eminent hospitals like Manipal Hospital, Apollo Hospitals and Narayana Hrudalaya in Bangalore.
He has experience of treating numerous colon cancer patients in Bangalore successfully .