Hirschsprung disease

In Hirschsprung disease Variable length of intestinal aganglionosis of the hindgut.   Rectosigmoid is the aganglionosis transition point for 80% of  Hirschsprung disease patients. Hirschsprung disease cab be Familial or sporadic. Up to 7.8% of Hirschsprung disease cases occur in patients for whom more than one family member is affected. Mutations in the RET protooncogene have […]