Glioblastoma (GBM) Treatment in Bangalore
Advanced glioblastoma surgery and treatment at Bangalore's top neuro-oncology centres.
Glioblastoma multiforme (GBM) is the most aggressive primary brain tumour, classified as WHO Grade 4. It arises from astrocytes — the star-shaped glial cells that support nerve cells. Despite its aggressive nature, Bangalore's neuro-oncology teams offer the most advanced treatment protocols including maximal safe resection with 5-ALA fluorescence guidance, concurrent chemoradiotherapy (Stupp protocol), tumour treating fields (TTFields), and clinical trials — giving patients the best possible outcomes.
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Symptoms of Glioblastoma (GBM)
Rapidly progressive headaches, often worse in the morning
Nausea and vomiting
New-onset seizures
Progressive weakness on one side of the body
Speech difficulties or confusion
Memory problems and personality changes
Visual disturbances
Fatigue and drowsiness
Causes & Risk Factors
Ionising radiation exposure (rare, but established risk factor)
Genetic syndromes: Li-Fraumeni syndrome, Lynch syndrome, NF1
IDH mutation status (IDH-wildtype GBMs are more aggressive)
MGMT promoter methylation (affects response to chemotherapy)
Most GBMs have no identifiable cause — they arise de novo
Treatment Options
Glioblastoma (GBM) Treatment in Bangalore
Bangalore's top neurosurgery hospitals offer the full spectrum of treatment options for Glioblastoma (GBM).
Maximal Safe Surgical Resection
Surgery aims to remove as much tumour as possible while preserving neurological function. 5-ALA fluorescence, intraoperative MRI, and awake craniotomy are used to maximise resection.
Concurrent Chemoradiotherapy (Stupp Protocol)
Standard of care after surgery: 6 weeks of radiotherapy with daily temozolomide chemotherapy, followed by 6 cycles of adjuvant temozolomide.
Tumour Treating Fields (TTFields)
Optune device delivers low-intensity alternating electric fields to disrupt tumour cell division. Approved for newly diagnosed and recurrent GBM.
Bevacizumab (Avastin)
Anti-VEGF therapy used for recurrent GBM to reduce tumour vascularity and control oedema.
Why Choose Bangalore for Glioblastoma (GBM) Treatment?
Bangalore's neuro-oncology centres offer multidisciplinary tumour boards, molecular profiling (IDH, MGMT, EGFR), and access to clinical trials. Manipal Hospital, Apollo, and Narayana Health City have dedicated neuro-oncology units with radiation oncologists, medical oncologists, and neurosurgeons working in integrated teams. Treatment costs are significantly lower than in Western countries while maintaining international standards.
Top Hospitals in Bangalore
Cost of Glioblastoma (GBM) Surgery in Bangalore
Surgery alone: ₹4–8 lakh. Full treatment including chemoradiotherapy: ₹10–15 lakh. TTFields device adds ongoing monthly costs. Insurance coverage varies.
Recovery Timeline
Post-operative monitoring. Steroids (dexamethasone) to reduce brain swelling. Neurological assessment.
Rest at home. Wound care. Steroid taper. Planning for chemoradiotherapy.
Daily radiotherapy (30 fractions) with concurrent temozolomide. Outpatient treatment.
6 cycles of adjuvant temozolomide. Regular MRI monitoring every 2–3 months.
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FAQ
Frequently Asked Questions
Common questions about Glioblastoma (GBM) surgery in Bangalore.