Monthly Archives: May 2013


Haploidentical Bone Marrow Donor

Why to chose the Haploidentical Bone Marrow Donor? The almost always present yet overlooked donor is the haplotype matched sibling, parent, or offspring. Haploidentical Bone Marrow Donor hematopoietic cell transplantation has been evaluated for more than two decades as an alternative option for the approximately 70 percent of patients who […]


Where are Stem Cells Found?

Where are Stem Cells Found? For human transplantation protocols, hematopoietic stem cells can be collected from a variety of sources including the marrow, blood, and umbilical cord blood obtained at the time of delivery. Bone Marrow: The major place Where are Stem Cells Found Marrow is the traditional source of […]


Principles of Hematopoietic Stem Cell Transplantation

General View of Hematopoietic Stem Cell Transplantation Over the past 60 years the field of hematopoietic stem cell transplantation  has evolved from experimental animal models of marrow transplantation to curative therapy for tens of thousands of people yearly who are affected by a wide variety of marrow failure states, myeloid […]


Hematopoietic Stem Cells Self-Renewal

Hematopoietic Stem Cells Division The ability to divide symmetrically to generate identical daughters is a feature of most cells, including hematopoietic stem cells. However, the multipotent stem cell possesses an added ability to undergo asymmetric cell divisions, yielding one committed progenitor daughter and one stem cell daughter, or two differentiating […]


Definition and Function of Bone Marrow Stem Cells

The Concept of Mother cell or Bone Marrow Stem Cells Although the concept of a common “mother cell” of all blood elements in the adult dates to Maximov in 1909, and its potential for participation in disease as proposed by Danchakoff in 1916, the basic concepts of a hierarchical organization of […]


Bone Marrow Stem Cells

The Embryonic origin of Bone Marrow Stem Cells The ontogeny of Bone Marrow Stem Cells is the focus of much attention. In fetal development the manufacture of blood occurs in various organs but after birth this function is subsumed by the marrow. Current evidence identifies early hematopoietic cells both in […]


Bone Marrow Testing

Bone Marrow Testing is the mainstay in Hematologic Diagnosis Microscopic examination of the marrow is a mainstay of hematologic diagnosis. Even with the advent of specialized biochemical and molecular assays that capitalize on advances in our understanding of the cell biology of hematopoiesis, the primary diagnosis of hematologic malignancies and […]


Bone Marrow Aspiration Technique

Technique of Bone Marrow Aspiration What you need to know about your anatomy before Bone Marrow Aspiration At birth, all bones contain hematopoietic marrow. Fat cells begin to replace hemopoietic marrow in the extremities in the fifth to seventh year. By adulthood, the hemopoietic marrow is limited to the axial […]


Indications of Bone Marrow Biopsy

What are the indications of Bone Marrow Biopsy? The International Council for Standardization in Hematology has published guidelines for bone marrow biopsy to promote consistency in performance and reporting. Although bone marrow biopsy techniques is safe, it should be performed with a clear idea as to how the results will help distinguish the […]


Bone Marrow: Overview

Bone marrow: What you need to know!  The bone marrow, located in the medullary cavity of bone, is the sole site of effective hematopoiesis in humans. The bone marrow produces approximately six billion cells per kilogram of body weight per day. Hematopoietically active (red) marrow regresses after birth until late […]


Acute Promyelocytic Leukemia

What is Acute Promyelocytic Leukemia? Acute Promyelocytic Leukemia is a variant of Acute Myelogenous Leukemia, which is called M3 in the FAB classification and acute promyelocytic leukemia in the WHO classification, occurs at any age and constitutes approximately 10 percent of Acute Myelogenous Leukemia cases. This subtype of Acute Myelogenous Leukemia occurs […]


Balloon Valvuloplasty Overview

Definition of Balloon Valvuloplasty Balloon valvuloplasty, also called percutaneous balloon valvuloplasty, is a surgical procedure used to open a narrowed heart valve. The procedure is sometimes described as balloon enlargement of a narrowed heart valve. Purposes of Balloon Valvuloplasty Balloon valvuloplasty is performed on children and adults who have a […]


Post Arteriovenous Fistula Complications

Arteriovenous Fistula Definition Arteriovenous Fistula for Dialysis Hemodialysis via Arteriovenous Fistula Hemodialysis Vascular Access Arteriovenous Fistula Surgery Post Arteriovenous Fistula Complications Arteriovenous Fistula Complications that are related to the vascular access The most frequent Arteriovenous Fistula complications in hemodialysis relate to the vascular access site where needles are inserted. Arteriovenous […]


Arteriovenous Fistula Surgery

Arteriovenous Fistula Definition Arteriovenous Fistula for Dialysis Hemodialysis via Arteriovenous Fistula Hemodialysis Vascular Access Arteriovenous Fistula Surgery Post Arteriovenous Fistula Complications Arteriovenous Fistula Surgery Steps Arteriovenous Fistula Surgery is usually done using a local anesthetic that is injected into the forearm at the site of the proposed fistula. The procedure […]


Hemodialysis Vascular Access

Arteriovenous Fistula Definition Arteriovenous Fistula for Dialysis Hemodialysis via Arteriovenous Fistula Hemodialysis Vascular Access Arteriovenous Fistula Surgery Post Arteriovenous Fistula Complications How can we define Hemodialysis Vascular Access? Hemodialysis Vascular Access is an access or entry to the vascular system is needed to perform the blood-cleansing role of the kidneys […]


Hemodialysis via Arteriovenous Fistula

Arteriovenous Fistula Definition Arteriovenous Fistula for Dialysis Hemodialysis via Arteriovenous Fistula Hemodialysis Vascular Access Arteriovenous Fistula Surgery Post Arteriovenous Fistula Complications Why to perform Dialysis? Dialysis is performed as critical life support when person experiences acute or chronic kidney failure. Hemodialysis via Arteriovenous Fistula is a mechanical way to cleanse the blood […]


Arteriovenous Fistula for Dialysis

Arteriovenous Fistula Definition Arteriovenous Fistula for Dialysis Hemodialysis via Arteriovenous Fistula Hemodialysis Vascular Access Arteriovenous Fistula Surgery Post Arteriovenous Fistula Complications What is the idea behind establishing an Arteriovenous Fistula for Dialysis? Dialysis is the process of mechanically cleansing the blood when the kidneys have failed. The surgical creation of […]


Arteriovenous Fistula Definition

Arteriovenous Fistula Definition Arteriovenous Fistula for Dialysis Hemodialysis via Arteriovenous Fistula Hemodialysis Vascular Access Arteriovenous Fistula Surgery Post Arteriovenous Fistula Complications Arteriovenous Fistula Definition An arteriovenous fistula Definition (AV fistula) is an abnormal connection between a vein and an artery. Depending on the Arteriovenous Fistula Definition, the connection can be […]


After Aortic Valve Replacement Care

Aortic valve replacement Overview Aortic Valve Replacement Surgery After Aortic Valve Replacement Care In Hospital After Aortic Valve Replacement Care   The patient will have continuous cardiac monitoring performed in the intensive care unit (ICU) postoperatively. Medications or mechanical circulatory assist may be instituted during the surgery or postoperatively to […]


Aortic Valve Replacement Surgery

Aortic valve replacement Overview Aortic Valve Replacement Surgery After Aortic Valve Replacement Care Steps of Aortic Valve Replacement Surgery First Step in Aortic Valve Replacement Surgery The first step in Aortic Valve Replacement Surgery is receiving general anesthesia in preparation for the surgery, the patient’s cardiac function will be monitored. […]


Aortic Valve Replacement Overview

Aortic valve replacement Overview Aortic Valve Replacement Surgery After Aortic Valve Replacement Care Aortic valve replacement Definition It’s known that Aortic valve replacement is the insertion of a mechanical or tissue valve in place of the diseased biological aortic valve. The purpose of Aortic valve replacement Aortic valve replacement is […]


Aortic Aneurysm Repair Complications

Aortic aneurysm repair overview Aortic aneurysm repair surgery Abdominal aortic aneurysm repair Thoracic aortic aneurysm repair Aortic aneurysm repair complications Aortic Aneurysm Repair Complications: Risks of General Anesthesia One of the Aortic Aneurysm Repair Complications are those risks which are associated with general anesthesia not associated with the aortic aneurysm […]


Thoracic Aortic Aneurysm Repair

 Aortic aneurysm repair overview Aortic aneurysm repair surgery Abdominal aortic aneurysm repair Thoracic aortic aneurysm repair Aortic aneurysm repair complications Thoracic Aortic Aneurysm Repair Definition Thoracic aortic aneurysm repair is the surgical repair of aneurysm that involves the ascending, arch, or descending thoracic aorta using the diaphragm as a landmark […]


Abdominal Aortic Aneurysm Repair

Aortic aneurysm repair overview Aortic aneurysm repair surgery Abdominal aortic aneurysm repair Thoracic aortic aneurysm repair Aortic aneurysm repair complications Definition of Abdominal aortic aneurysm repair Abdominal aortic aneurysm repair is defined as the surgical repair of the aneurysm that involves the descending aorta from the diaphragm to the point at […]